Michael R. Talcott, DVM, DACLAM

Division Director, Veterinary Surgical Services

Research Assistant Professor, Surgery and Neurosurgery

Washington University, St. Louis, Missouri

§ DVM (Veterinary Medicine), Michigan State University

§ BS, Physiology, Michigan State University

§ Postdoctoral fellowship in Laboratory Animal Medicine, Bowman Gray School of Medicine and University of Alabama-Birmingham

§ Diplomate, American College of Laboratory Animal Medicine

Research:

Dr. Talcott has collaborative research projects in cardiac electrophysiology and cardiac ablation models, vascular surgery, orthopedic surgery including lumbar and cervical spine fusion models, fetal tissue transplantation in diabetes. His surgical facility supports various surgical disciplines including minimally invasive surgery, cardiology, cardiothoracic surgery, orthopedics, neurosurgery, urology, plastic surgery, pediatrics and emergency medicine. The service provides anesthesia support and perioperative care for approximately 500 cases annually utilizing rabbits, pigs, dogs, sheep and goats.

Research Focus:

§ cardiac electrophysiology

§ animal models in orthopaedics

§ surgical animal models

§ lab animal medicine

§ comparative medicine

MTalcott@wustl.edu

Selected Publications:

Mayse ML, Parikh PJ, Lechleiter KM, Dimmer S, Park M, Chaudhari A, Talcott M, Low DA. Bradley JD (2008). Bronchoscopic implantation of a novel wireless electromagnetic transponder in the canine lung: a feasibility study. Int J Radiat Oncol 72(1):93-98.

Okubadejo GO, Talcott MR, Schmidt RE, Sharma A, Patel AA, Mackey RB, Guarino AH, Moran CJ, Riew KD (2008). Perils of intravascular methylprednisolone injection into the vertebral artery. An animal study. J Bone Joint Surg Am 90(9):1932-1938.

Taylor BA, Okubadejo GO, Patel AA, Talcott MR, Imamura T, Hu N, Cunningham BW (2008). Evaluation of total disc arthroplasty: a canine model. Am J Orthop 37(4):E64-70.

Person B, Vivas DA, Ruiz D, Talcott M, Coad JE, Wexner SD (2008). Comparison of four energy-based vascular sealing and cutting instruments: A porcine model. Surg Endosc 22(2):534-538.

Rogers SA, Chen F, Talcott MR, Faulkner C, Thomas JM, Thevis M, Hammerman MR (2007). Long-term engraftment following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic rhesus macaques. Xenotransplantation. 14(6):591-602

Perin EC, Munger T, Pandey A, Talcott M, Birchard C, Creed J, Wong J, Angeli F, Sanz R, Fernandes M, Oliveira E, Jimenez-Quevedo P, Silva GV (2007). First Experience with Remote LV Mapping and Injection Utilizing a Novel Integrated NOGA XP/Stereotaxis Platform. EuroInterv. 3:142-148.

Rogers SA, Chen F, Talcott MR, Faulkner C, Thomas JM, Thevis M, Hammerman MR (2007) Long-term engraftment following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic rhesus macaques. Xenotransplantation. 14(6):591-602.

Rogers SA, Chen F, Talcott M, Liapis H, Hammerman MR (2006). Glucose tolerance normalization following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic ZDF rats. Transpl Immunol 16(30-34):176-184. (Erratum appears in Transpl Immuno 2007 17(4):288-289.)

Anderson CD, Talcott M (2006). Clinical Practice versus Field Surgery: A Discussion of the Regulations and Logistics of Implanting Radiotransmitters in Snakes. Wildlife Soc B 34(5):1470-1471.

Greenberg S, Blume W, Faddis M, Finney J, Hall A, Talcott M, Lindsay B (2006). Remoter Controlled Magnetically Guided Pulmonary Vein Isolation in Canines. Heart Rhythm 3(1):71-76.

Gopalan C, Hegade GM, Bay TN, Brown SR, Talcott MR (2005). Tribromoethanol-Medetomidine Combination Provides a Safe and Reversible Anesthetic Effect in Rats. ContempTop Lab Ani 44(1).

Talcott M, Corey M (2004). Developing and maintaining a surgical research program: surgical suite design. Lab Animal 33 (6): 28-33.

Talcott M, Corey M (2004). Developing and maintaining a surgical research program: surgical suite design. Lab Animal 33 (6): 28-33.

Talcott M, Corey M (2004). Developing and maintaining a surgical research program: surgical suite design. Lab Animal 33 (6): 28-33.

Lewis A, Talcott M (2004). Maintaining the surgical research facility: the role of the surgical technician. Lab Animal. 33(6): 39-42.

Diaz S, Uzieblo MR, Desai KM, Talcott MR, Bae KT. Geraghty PJ Parodi JC Sicard GA Sanchez LA Choi ET (2004). Type II endoleak in porcine model of abdominal aortic aneurysm. J Vasc Surg 40(2):339-344.

Ratnaraj J, Kabon B, Talcott MR, Sessler DI, Kurz A (2004). Supplemental oxygen and carbon dioxide each increase subcutaneous and intestinal intramural oxygenation. Anes Analg 99(1):207-211.

Rogers SA, Chen F, Talcott M, Hammerman MR (2004). Islet cell engraftment and control of diabetes in rats after transplantation of pig pancreatic anlagen. Am J Physiol Endoc M 286(4): E502-509.

Faddis MN, Chen J, Osborne J, Talcott MR, Lindsay B (2003). Magnetic Guidance System for Cardiac Electrophysiology: A Prospective Trial of Safety and Efficacy in Humans. JACC 42(11):1952-1958.

Rogers SA, Talcott M, Hammerman MR (2003). Transplantation of pig metanephroi. ASAIO J 49(1): 48-52.

Faddis MN, Blume W, Finney J, Hall A, Rauch J, Sell J, Bae KT, Talcott M, Lindsay B (2002). Novel, Magnetically Guided Catheter for Endocardial Mapping and Radiofrequency Catheter Ablation. Circulation 106(23): 2980-2985.

Greco SC, Talcott MR, LaRegina MC, Eisenbeis PE (2001). Use of Intraosseous blood for repeated hematological and biochemical analyses in healthy pigs. Am J Vet Res 62(1): 43-47.