Associate Professor
PhD, Iowa State University
Research emphasis: Dr. Rottinghaus's research focuses on using chromatographic techniques for developing new analytical methodology as well as isolation, purification of a number of natural products. Major interests have centered on fungal metabolites (mycotoxins), Tall Fescue alkaloids (ergovaline) and phyto and fungal estrogens. He has produced a number of important mycotoxins (T-2 toxin, diacetoxyscirpenol, aflatoxin, fumonisin, ochratoxin A, zearalenone and moniliformin) in large quantities from fungal culture for animal feeding studies in cattle, swine, chickens, turkeys, ducks, mink, catfish, and laboratory animals. Current research involves in vitro and in vivo examination of natural sorbents and fermentation products for decontaminating and remediation of animal feeds containing high levels of mycotoxins and developing rapid analytical methodology for the active components of medicinally important plants.
He is in charge of the Analytical
Core Facility for the MU Center for Phytonutrient and Phytochemical Studies
(MUCPPS) and is part of the research group that makes up the Fusarium/Poultry
Research Laboratory at the University of Missouri.
Teaching: Veterinary Analytical Toxicology Lectures
Selected publications:
Tuan NA, Manning B, Lovell RT, and Rottinghaus GE. Responses of Nile Tilapia (Oreochromis niloticus) fed diets containing different concentrations of moniliformin or fumonisin B1. Aquaculture 217(1-4):515-528, 2003.
Gray DE, Pallardy SG, Garrett HE, and Rottinghaus GE. Acute drought stress and plant age on alkamide and phenolic acid content in purple coneflower roots. Planta Medica 69(1):50-55, 2003.
Manning BB, Ulloa RM, Li MH, Robinson EH, and Rottinghaus GE. Ochratoxin A fed to channel (Ictalurus punctatus) causes reduced growth and lesions of hepatopancreatic tissue. Aquaculture 219:739-750, 2003.
Kallenbach RL, Bishop-Hurley GJ, Massie MD, Rottinghaus GE, and West CP. Herbage mass, nutritive value, and ergovaline concentration of stockpiled tall fescue. Crop Sci 43:1001-1005, 2003.
Dokovic A, Tomasevi-Anovi M, Rottinghaus G, Dondur V, and Magi Z. Adsorption of ochratoxin A on octadecyldimethyl benzyl ammonium exchanged-clinoptilolite-heulandite tuff. Colloids and Surfaces B: Biointerfaces 30 (1-2): 157-165, 2003.
Al-Tamimi HJ, Rottinghaus GR, Spiers DE, Spain J, Chatman D, Eichen PA, and Carson TL. Thermoregulatory response of dairy cows fed ergotized barley during summer heat stress. J Vet Diagn Invest 15:355-360, 2003.
Constable PD, Smith GW, Rottinghaus GE, Tumbleson ME, and Haschek WM. Fumonisin induced blockade of ceramide synthase in the sphingolipid biosynthetic pathway alters the aortic input impedance spectrum of pigs. Am J Physiol- Heart and Circulatory Physiology, 284:H2034-H2044, 2003.
Kumar A, Jindal N, Shukla CL, Pal Y, Ledoux, DR, and Rottinghaus GE. Effects of ochratoxin A. on Escherichia coli challenged broiler chicks. Avian Dis, 47:415-424, 2003.
Tomasevi-Anovic M, Dakovic A, Rottinghaus G, Matijsevi S, and Duricic M. Surfactant modified zeolites? New efficient adsorbents for mycotoxins. Microporous and Mesoporous Materials 61:173-180, 2003.
Tomasevi-Anovi M, Dokovi A, Rottinghaus G, and Arov-Stan A. Adsorption of ochratoxin A by octadecyldimethylbenzyl-heulandite tuff. Microporous and Mesoporous Materials. 2003.
Youn HJ, Lakritz J, Kim DY, Rottinghaus GE, and Marsh AE. Anti-Protozoal efficacy of medicinal herb extracts against Toxoplasma gondii and Neospora caninum. Veterinary Parasitology, 2590:1-8, 2003.
Oliveira JA, Rottinghaus GE, and Gonzalez E. Ergovaline concentration in two perennial ryegrass genotypes infected with a lolitrem B-free fungal endophyte over a three-year period in Northwest Spain. New Zealand Journal of Agricultural Research 46(2):117-122, 2003.
Watts CM, Chen YC, Ledoux DR, Bermudez AJ, and Rottinghaus GE. Effects of multiple mycotoxins and a hydrated sodium calcium aluminosilicate in poultry. International J Poultry Science, 2(6):372-378, 2003.
Ledoux DR, Broomhead JN, Bermudez AJ, and Rottinghaus GE. Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin, in broiler chicks. Avian Diseases 47:1368-1375, 2003.
Gray DE, Pallardy SG, Garrett HE, Rottinghaus GE. Acute drought stress and time of harvest on phytochemistry and dry weight of St. John’s Wort leaves and flowers. Planta Medica 69:1024-1030, 2003.
Curran EM, Judy BM, Newton LG, Lubahn DB, Rottinghaus GE, MacDonald RS, Franklin C, and Estes DM. Dietary soy phytoestrogensand ER alpha signaling modulate interferon gamma production in response to bacterial infection. Clinical & Experimental Immunology 135(2):219-225, 2004.
Guo JY, Li X,
Browning JD, Rottinghaus GE, Lubahn DB, Constantinou A, Bennink M, and MacDonald
RS. Dietary soy isoflavones or estrone protect from carcinogen-induced colon
cancer in ERaKO and wild type mice. J Nutrition 134(1): 179-182, 2004.